Automatically filter, mix, heat, degas & dispense your dissolution media accurately with the DosaPrep X8.
DissoPrep X8 Media Degasser
Dissolution Media Preperation and Delivery Station - the perfect solution!
Efficient • Reproducable • Safe
The DissoPrep X8 has been designed to quickly and safely remove dissolved gases in dissolution media. Fully compliant with the USP, EP, FDA, GLP/GMP recommendations and regulations, it is capable of processing up to 8 litres of dissolution media in a single operation.
- Automated preparation and dispensing of dissolution media
The media, which may be a combination of water and acid or buffer, is filtered, mixed, warmed and degassed under vacuum and dispensed in up to 8 individual volumes with an accuracy of better than ±5 grams. The complete sequence is accurately monitored and each dispensed volume can be printed out or sent to a computer for extra validation documentation.
- Time and cost saving
With the DissoPrep X8 media mixture, degassing and preheating can be performed without user intervention. Precise media dispensing directly into the sample vessels saves time and unnecessary media handling. Preheating the media saves time between tests and increases throughput.
- Acid mixing
For the precise addition of concentrated hydrochloric acid (max. 36%) a second liquid channel is available. The composition calculation is carried out gravimetrically via a precision balance. The risk associated with working with acidic media is minimised.
- Filtering
An easily exchangeable in-line filter cartridge is located within the fill tube. The capacity of the filter is checked automatically by monitoring the total volume filtered and the resulting flow resistance. The system prompts the user to change the filter when the capacity is exceeded.
- Heating
A special continuous-flow heater warms the media to the desired temperature (±2°C) before degassing takes place. This promotes improved degassing and saves considerable time when heating in the dissolution tester.
- Stirring and Mixing
An electronic stirrer moves the media in the storage tank and ensures an homogenous acid concentration.
- Degassing
Optimum degassing is achieved by exposing the warmed incoming media to a constant vacuum of better than 700mbar below atmospheric pressure, and continuous stirring.
- Quickly fills and dispenses
The processing of 8 litres of media is complete within 15 minutes. In order to save time, media can even be prepared while a test is running. Each vessel is filled directly into the dissolution tester by means of a dispensing tube. High precision dispensing (±0.5%) requires approximately 25 seconds to dispense 1000ml. The target volume can be selected between 400 and 1000ml.
- Safety in the laboratory
By automating the process, particularly the acid preparation and media dispensing, the risk to laboratory personnel is minimised.
Specifications | |
Dosing volume: | 400-1000ml (dispensed by weight) per vessel |
Storage tank volume: | 8000ml net, 11000ml gross |
Heating capacity: | Up to Δ20°C |
Temperature accuracy: | ±2°C |
Input channels: | 2, for water or pre-mixed media and acid or buffer |
Maximum input pressure: | 0.1 bar |
Maximum acid concentration: | 36% concentration at the acid input 0.5% concentration for mixed media input/output |
Dispensing principle: | By precision weighing |
Dispensing accuracy: | Better than ±5g |
Degassing: | Under vacuum |
Mixer: | Magnetic stirrer |
Input filter: | Cartridge filter 20µm: Filter-Capsule Sartorius type 5591320P5--00 |
Printer Output: | Centronics (parallel) |
PC Interface: | RS-232 (serial) |
Dimensions (W × H × D): | 300 × 660 × 590mm |
Weight: | 27kg |
Electrical requirements: | 2400 Watt at 230V, 1800 Watt at 115V (up to 16A) |
Click to download a copy of the DissoPrep Brochure
